June 23, 1846

Dmd065482 1838..1846

UDP-Glucuronosyltransferases (UGTs) conjugate a glucuronyl group from glucuronic acid to a wide range of lipophilic substrates to form a hydrophilic glucuronide conjugate. The glucuronide generally has decreased bioactivity and increased water solubility to facilitate excretion. Glucuronidation represents an important detoxification pathway for both endogenous waste products and xenobiotics, in...

ECCP WG Ships – Meeting 2 on 22-23 June 2011

Introduction Although preferring a global solution for a market-based measure for curbing CO2 emissions from international shipping, the European Union has indicated that it will implement its own policies if no global agreement can be reached. EU Directive 2009/29/EC sets a deadline for a global agreement by stating that “In the event that no international agreement ... has been approved ... b...

George Rosen, M.D., Ph.D. (June 23, 1910-July 27, 1977).

On July 27, 1977, George Rosen died suddenly in Oxford, England. He and Mrs. Rosen had planned to travel leisurely through the English countryside, enjoying themselves as they had so often in the past, and ultimately to arrive in Scotland in time for Professor Rosen to deliver a keynote address and participate in a symposium on "Medicine and Industrialization in History" [1]. Professor of the H...

George Wells Beadle - 23 October 1903--9 June 1989.

Multiple Fentanyl Overdoses — New Haven, Connecticut, June 23, 2016

On the evening of June 23, 2016, a white powder advertised as cocaine was purchased off the streets from multiple sources and used by an unknown number of persons in New Haven, Connecticut. During a period of less than 8 hours, 12 patients were brought to the emergency department (ED) at Yale New Haven Hospital, experiencing signs and symptoms consistent with opioid overdose. The route of intox...